OGB

 
METRONIDAZOLE

Infusion

 
:: COMPOSITIONS ::

Each bottle (100 ml) METRONIDAZOLE
infusion contain:
Metronidazole 500 mg

 
:: INDICATIONS ::
  • Infections caused by anaerobic or other metronidazole-sensitive bacteria.
  • Prophylaxis of pre- and post-op anaerobic infections.
  • Amoebiasis, trichomoniasis
 
:: DOSAGE AND ADMINISTRATION ::

Infections due to anaerobic bacteria
Adult: initially 15 mg/kg body weight by IV, followed by maintenance dose of 7.5 mg/kg body weight/6 hours.
Maximum daily dose: 4 g/day (IV or orally). Duration of treatment: 7 days. 

Prophylaxis of pre- & post-op infections
Adult: 15 mg/kg body weight by IV infusion for 30-60 minutes until 1 hour before surgical procedure.
If needed, 7.5 mg/kg body weight by IV infusion for 30-60 min at 6 and 12 hours after initial dose. Infusion of pre-op initial dosage should be finished 1 hour before operation.

Alternative for peri operative prophylaxis in colorectal surgery
500 mg-1 g IV infusion 1 hour before surgery and 500 mg IV infusion 8 and 16 hours after surgery.

 
:: CONTRAINDICATIONS ::
  • Hypersensitivity to metronidazole or other nitroimidazole derivatives.
  • 1st trimester of pregnancy.
 
:: WARNING AND PRECAUTION ::

CNS disorders, blood dyscrasia, avoid alcohol, severe liver dysfunction, children, elderly and lactation.

 
:: ADVERSE REACTIONS ::

Nausea, vomiting, abdominal discomfort, metallic taste, diarrhea, peripheral neuropathy, transient leucopenia & thrombocytopenia, bone marrow aplasia, dark urine, erythematous rash, pruritus, photosensitivity, thrombophlebitis, hypertension, myocardial infarction, rheumatoid arthritis.

 
:: PRESENTATION AND REGISTRATION NUMBER ::

Box, bottle @ 100 ml;